Knowledge Management System (KMS) has been receiving considerable attention in this decade and information technology (IT) is emphasized in KMS literature. Organizational members’ interpretation toward IT, however, may strongly influence the results of IT introduction and implementation. This research perceives that this perspective is seldom explored in KMS literature thus investigates a Taiwanese IC testing company to study how its members’ interpretations toward a KMS technology would cause the resistance. This research adopts Orlikowski & Gash’s technological frame as a theoretical background to conduct the interpretive research. Related data collecting was mainly through unstructured interview(s). The result shows that there have been three different categories of interpretation (MIS manager, board masters, general users and system developers) toward the KMS technology. This research argues that the difference of interpretation among the three produced an undiscussable conflict and hence the consequent behavior marked down the usage of KMS. This research also attempts to find out how their interpretations were formed based on data available. This research also holds that though technological frame can reveal what one’s interpretations are, it cannot tell us how they are formed.